marsden fund recipients

The study takes a multimethodological approach to the topic, with an overall ethnographic lens. This will show how Pacific cultures expand our understanding of human psychology and how text analysis can identify structure and variation in human cognition. The Marsden Fund (the Fund), established in 1995, invests in excellent investigator-led research. So called “successful” psychopathy in the community is poorly understood. There are over 500 whai patterns yet most current practitioners would struggle to produce 20, let alone know the individual chants, prayers and associated narratives embedded within whai. Fruit body differentiation in mushrooms and truffle-like fungi $960,000. View more on how to contact us or use this form to send us an email. How to be reimbursed All the subsistence up to the maximum fund for the award recipient set by the committee is reimbursed by receipts and following ACM processes for reimbursement. The main ingredient which has not been used in other numerical approaches is the application of a powerful mathematical trick, which is rooted in conformal geometry: one can redefine what time and space mean without changing the physical properties of the simulated system. The large range of genome sizes, and the corresponding number of proteins and RNAs, leads to a combinatorial explosion of potential molecular mis-interactions in crowded cells. While this work is basic science in a model organism, this novel approach may have wide reaching implications for designing strategies for regenerative medicine in the future. Here, the team propose to study the molecular mechanism of the lncRNA lncTNBC1, a previously uncharacterised cytoplasmic lncRNA, which significantly impacts cancer cell growth. However, it is becoming apparent that many bacteria and viruses also use compartments. We wish all recipients – from both Otago and elsewhere – every success in their research endeavours.”, With a little help from my friends: how do symbiotic microorganisms influence regenerative outcomes? A maximum fund for each award recipient is decided by the fund committee based on the application review and the available fund quota. All the subsistence up to the maximum fund for the award recipient set by the committee is reimbursed by receipts and following ACM processes for reimbursement. Thus the results obtained will be of wide interest to both the dispersive equations, and harmonic analysis communities. Marsden fund recipient Professor Peter Adams from the Centre for Addiction Research plans to look closely at the power of industries like tobacco and alcohol to influence policy makers. Based on preliminary data on this tumour-specific molecule, they hypothesise that lncTNBC1 acts by binding to other RNA molecules in the cell, thereby modulating protein synthesis of essential cell growth regulators. They account for a substantial share of the earth’s biomass, represent up to half of all species, and are involved in 50-75 per cent of food web trophic interactions. 101 science teams from across the country are to receive support from the almost $56 million available in grants from prestigious The Marsden Fund. This project will address this problem for important model equations in mathematical physics (in particular nonlinear Dirac and Zakharov systems) by developing new multilinear restriction estimates. Exploring the epigenetic mechanisms by which maternal nutrition and metabolism influence prenatal development $960,000. One particular question is whether it is possible to deform a black hole to such an extreme that it would cease to be a black hole and transform into something else. Current practice for detection of gastrointestinal (GI) disorders involves imaging the GI tract lining through endoscopic imaging and biopsy collection. Among the Massey University Marsden Fund recipients are Dr Rachel Blagojevic and Dr David Aguirre (below) $5.1m in Marsden grants for Massey researchers Ten Massey University-led research projects will receive research funding worth more than $5.1 million from the Government's Marsden Fund … Announced this week, a total of 109 research projects have been allocated $59 million of funding in this year’s Marsden Fund grants. A total of 22 research projects at Otago received funding in this year's round, between them accounting for about a quarter of the money the Marsden Fund provided to the university sector this year. They will test experimentally if these changes are sufficient to turn mushrooms into truffles in the laboratory using model truffle/mushroom species pairs. The nature of this expansion is slowly becoming understood. Raman spectroscopy, a light based and non-destructive method, has been demonstrated as a potential cancer detection method. Understanding the global in time behaviour of nonlinear dispersive partial differential equations is a major open problem. From my own experience, I know the transformative effect that the peer recognition and funding that are associated with being a Marsden Fund recipient can have. Can we adopt this different, more effective architecture to improve computer vision? Pandemic, Pasifika health and asthma research among Massey's Marsden successes Clockwise from top left: Professor Joachim Brand, Professor Murray Cox, Professor Jeroen Douwes, Dr Andrea Clavijo-McCormick, Dr Katherine Holt, Dr Wesley Webb, Professor Mick Roberts, Dr Ridvan Firestone, Dr Rochelle Stewart-Withers and Dr Nikki Freed. The composition of the microbiome is known to affect our health in many ways, from ability to digest foods, to risk of developing Alzheimer’s. Cross-cultural Patterns in Theory of Mind: Using text analytics to identify structure and variation in mental state attributions in the Pacific $300,000. Controversy surrounds the role of competition during lineage diversification. Māori string figures are known as “whai”, from “te whai wawewawe ā Māuitikitiki-ā-Taranga” – to follow in the deft footsteps of the mythical hero Māui. The enzymatic addition of methyl groups to DNA and their removal is an integral part of epigenetic programming. Artificial intelligence (AI) and machine learning pose enormous potential for improving quality of life but also significant social, cultural and other risks. Deputy Vice … But what happens when multiple parasites infect one host: do they conflict or collaborate? Dr Dowle’s team propose to couple phenotypic and behavioural assays with powerful molecular techniques to reveal the mechanism(s) that conspecific co-occurring parasites employ to help or hinder each other’s development. Te whai wawewawe ā Māuitikitiki-ā-Taranga: Revitalisation of Māori string figure knowledge and practice $842,000. In this project the researchers develop theory for the next generation of this system – the binary magnetic gas – a mixture of two magnetic fluids with rich intercomponent physics and controllable immiscibility. Identification of shared genetic pathways can reveal mechanisms underlying development of complex structures. The Marsden Fund Council manages the Marsden Fund on behalf of the Minister of Science and Innovation. Controlling invasive species, at a cost of NZ$1.4 billion annually, depends upon ongoing public awareness and support. Major gaps still remain, particularly on the island of New Guinea where there is a consensus that Austronesian speakers bypassed it on their way to Remote Oceania. This “affirmative consent” model — only yes means yes, rather than no means no — has been adopted in a number of jurisdictions, and is gaining increased support, in light of anti-coercion/harassment cultural movements such as #MeToo, as a means of protecting sexual autonomy. From the University’s initial 166 proposals, it had a success rate of 16 percent, compared with a national rate of 11.5 percent. In New Zealand, a recent judicial split on the question highlights a pressing need for review of consent and reasonable belief in consent in sexual violence law, and whether rape law should be reformulated based on evolving social norms about access to the bodies of others. The Marsden Fund is the premiere funding mechanism for basic research in New Zealand. Recent evidence suggests it can also influence healing and regeneration in vertebrates. It is funded by the government, but selection and administration is delegated to … Dr Larcombe’s team recently produced the first empirical evidence that bounded and unbounded processes contribute equally to diversification, and they hypothesise that they do so by operating along different ecological niche axes. This project tests this new hypothesis. This project will use text analytics to build a database of mental state attributions in Pacific cultures. Sleep loss in children: perchance to eat? Specifically, it will be the first commensal study in the Pacific to investigate what nuclear DNA can tell us about the origins and admixture of Pacific people, which is not possible using mtDNA alone. To elicit donations, campaigners must share images and stories of illness online, for an audience of both friends and strangers… turning compassion into capital. This battleground for genetic supremacy is further complicated by the role of kin selection whereby closely related co-occurring hairworms may sacrifice their own survival for that of a close relative. Religion is ubiquitous, yet the fundamental question of how religion affects people remains unclear. In the stiped state the two components of the gas spontaneously separate and self-organise into a set of interleaved fingers. These are open to established researchers as well as emerging researchers. They will address crucial gaps in knowledge of the assembly of fruiting bodies and will improve understanding of convergent evolution within ecologically relevant organisms. Marsden Fund Fast-Start grants support early career researchers to develop independent research and build exceptional careers in New Zealand. $852,000. Several infectious bacteria exist that contain incomplete respiration pathways and it has historically been assumed that they don’t generate energy by respiration. Dr Collins’ team propose to apply the latest aDNA techniques to the commensal model, to generate new genomic data from modern and ancient Pacific rats and ancient chickens to greatly improve the resolution of our data compared to existing datasets. University of Otago researchers are the recipients of an inaugural Marsden Fund Council Award worth $3 million to investigate genetic predisposition to metabolic diseases like diabetes and gout among Pacific people. Meet Marsden 25 recipient Associate Professor Nick Golledge, from the Antarctic Research Centre at Te Herenga Waka—Victoria University of Wellington. Using a New Zealand freshwater trematode and its multiple hosts (a snail, an amphipod and a fish) in a combined ecology and isotope chemistry study, the team will accurately calculate the trophic position of each life-stage of a parasite’s life cycle, and investigate the impact of the different life-stages (endoparasitic and free-living) on energy flow through a freshwater food web. Each hairworm manipulates the host to optimise its own survival and reproductive opportunities, but what is optimal for one hairworm may not be optimal for all. The number of award recipients and the maximum fund for each recipient are decided by the deciding committee based on the application review. Current datasets are also not sufficient to understand the settlement of Central and East Polynesia. 2. The Longitudinal Study of Cohesion and Conflict: Testing Hypotheses of Social and Religious Change in Fiji $300,000. How to fit parasites in food webs? University of Otago researchers are the recipients of an inaugural Marsden Fund Council Award worth $3 million to investigate genetic predisposition to metabolic diseases like diabetes and gout among Pacific people. Humans depend on dietary vitamin C, and insufficient intake is common. Many bacteria generate energy for growth by a process called cellular respiration. [10] [11] [12] [13] Epigenetics reflects the interaction of nature (genetic inheritance) and nurture (environmental influence) and has captured the imagination of biologists, epidemiologists, social scientists, philosophers, health professionals and nutritionists. Through a combination of microbiome analysis, genetic engineering of Toll-like receptors, and manipulation of the skin microbiome, the research will establish both the mechanism of this response and the potential for cultivating a pro-regenerative microbial community. This is notoriously difficult because of a lack of identifiability: in most current models the two competing representations of spatial variation yield identical predictions, and therefore cannot be distinguished even with unlimited data. Piecing together Pacific prehistory using genomics and the commensal model $300,000. Dr Brown and his team propose to investigate fully this novel way of stopping using a combination of bioinformatic, transcription assays, and genetic approaches in bacteria. Many of these factors trigger gout flares. The ecology diversification: do processes that promote and constrain diversification operate along different niche axes? faces) in birds. Employing a kaupapa Māori approach, our all Māori research team will examine the knowledge system and practice of whai, develop best practice intergenerational transfer of whai knowledge and appropriate storage of whai knowledge for Aotearoa and the Pacific. At room temperature, the observed pace at which this happens is an average over a large range of collision energies which blurs the picture of what is going on. Information for grant recipients Marsden at 25. Development and assessment of a multi-spectroscopic fiber optic probe capable of disease diagnosis in the gastro-intestinal tract $300,000. The Δ133p53 isoforms are normally present in a small subpopulation of cancer cells and are expressed at high levels by cells surviving initial drug treatment. That the nutritional status of the mother can affect the lifelong health of the developing foetus has created great interest in how these processes work and in whether specific nutrients can impact epigenetic mechanisms of development in utero. Through this research, they expect to open up this new area of study, and potentially provide novel targets for antibiotics. This research will investigate the ability of group B streptococci, bacteria with partial respiration pathways and a cause of severe infections in newborns, to perform interspecies electron transfer at the molecular level. Our work will be vital in revitalising this unique, complex mnemonic system that documents and transmits Māori knowledge and practice. We performed functional and phenotypic characterisation of ion transport in the human pulmonary epithelial cell lines NCI-H441 and A549 to determine the … The ultimate goal is to translate their discoveries into greatly enhanced computer-vision software. This project’s novel approach using stable isotopes of amino acids as specific biomarkers will provide considerable insight into parasites’ role and dynamics within a food web. The results will enable future hypotheses to be tested about the factors driving the evolution of truffle-like fruiting bodies. These intriguing questions are a just a few of the problems being tackled by the recipients of this year’s round of grants from the Marsden Fund – New Zealand’s largest ‘blue skies’ research funding body. Recent theoretical research suggests that mis-interactions place major limits on protein and RNA sequence evolution, and selects for sequences that can avoid mis-interactions while still maintaining function. Actually, not any more! This ‘blue-sky’ funding is vital to ensuring a vibrant research culture in our country, and the resulting work will help us better understand our environment and society. The repeated parallel evolution of truffle-like fungi is an excellent model system in which to discover such common genetic mechanisms. We will also determine if sleep loss changes energy balance through promoting more sedentary behaviour and less physical activity (7-day actigraphy/motion sensor). In total, 23 University of Auckland submissions were awarded Marsden Fund Standard grants. Is the overlap between gout flare triggers and environmental influencers of epigenetic marks a coincidence? Computer vision is part of our daily life, and saves lives by detecting hazards in industrial workplaces and reducing or eliminating human errors in demanding tasks, such as driving vehicles. A central focus is the role of ‘moral emotions’ (e.g. Specifically, they will manipulate individual sleep patterns of 110 children aged 8-12 years so each child receives one week of sleep restriction (1h less time in bed than usual) and sleep extension (1h longer), with one week washout in between (resume normal sleep) whilst undertaking repeated assessments of outcomes of interest: eating in the absence of hunger within an ad libitum feeding experiment at the end of each experimental week; eating behaviours (appetite regulation, eating for reasons other than hunger); type, quantity and timing (24-hour recalls); context of eating including hidden eating (using novel wearable cameras) and desire for treat foods (computerised task). A new generation of statistical models for spatial point process data $705,000. Marsden Fund Council Chair Professor David Bilkey says: “The Marsden Fund is designed to enable our top researchers to develop their most ambitious and exciting ideas. In all, 88 research projects have been allocated a total of $53.8 million from the contestable government-funded Marsden Fund. We aim to test the hypothesis that the pituitary hormone prolactin, which we have recently shown is critical for maternal behaviour, has an analogous function in the male. But not all campaigns are successful. Genome-wide studies revealed the presence of up to 100,000 genes encoding for long non-coding RNAs (lncRNAs) in the human genome. This innovative study will pioneer the transfer into this emerging AI field of equity concepts that have been well-developed in social disciplines, creating novel fairness algorithms. The Marsden Fund Council is appointed by the Minister of Science and innovation. Dr Major’s team hypothesises that environmental factors are triggering gout flares through their influence on epigenetic control of the innate immune system. Yet, work by archaeologists at Otago is leading to a serious rethink of this expansion. The role of fathers in promoting healthy development of their offspring is acknowledged, but just what is happening in the paternal brain during this important process is largely unknown. Professor Colombo’s team aim to bring New Zealand to the forefront of the biology: technology interface to facilitate the development of computer-vision architecture with mechanisms derived from the incredibly powerful avian visual system. Dissemination of findings will involve local communities in applied policy recommendations. Parasites are a ubiquitous component of all ecosystems. Truffle-like fungi evolved independently many times to rely on animals to disperse their spores, rather than wind like their mushroom ancestors. Siblings share (roughly) half their genes, and are often raised in the same environment. The origins of the Lapita people, and their interactions with other people in the Pacific, remain unclear. The grants were among $13.7million to be awarded to 23 Otago University research projects by the fund which supports investigator-initiated research. $300,000. 362 Leith Street The repeated evolution of similar physiological and morphological traits occurs throughout life. New Zealand faces a huge ecological problem from invasive plants and animals spreading across the country impacting native species and landscapes – a problem expected to grow with climate change. The Otago gravity group led by Professor Frauendiener has developed a powerful numerical framework for analysing situations like this where one needs to follow the development of a system for a long time and over large distances. What makes a psychopath? Their investigations in the ultracold domain will provide new insight into how more complex chemical reactions can be probed and controlled. Principal investigators, Professors Tony Merriman and Lisa Matisoo-Smith and Dr Anna Gosling from Otago join Associate Professor Frank Camacho from the University of Guam and … Since then, there has been no extensive examination of whai, let alone widespread use of it. Are molecular mis-interactions a major constraint on the evolution of cellular and genomic complexity? Today, whai is a culturally important art and knowledge system close to extinction. However, the virulence of these bacteria depends on the presence of these partial respiration steps. Their results will contribute to unravelling new functions of cytoplasmic lncRNAs in the cell and their potential as new prognostic and/or therapeutic targets in cancer. Read about highlighted projects and announcements for each funding round Search Marsden awards 2008–2017. To do so, they harness separated, nanokelvin-cold molecular gas clouds in test tubes of light formed by optical tweezers - a tool that won the 2018 Nobel Prize in Physics. Neuroscience already explains many mental processes. In New Zealand, diabetes and cardiovascular diseases are the leading causes of premature death and disease burden and major sources of health inequities for Māori, Pacific, and Asian populations due to socio-economic, cultural and health system factors. Preliminary data implicate oncogenic Δ133p53 isoforms of the p53 tumour suppressor gene as central regulators of drug tolerance. The aim of the proposal is to investigate the hormonal basis of parental behaviour in males. sympathy, pity, or contempt) on social media, and how these might connect and position people. Comparative genomics and transcriptomics will be used to identify the hypothesised genetic alterations for the switch between mushrooms and truffles. They will study the organisation dynamics and explore if the striped phase realises an elusive supersolid state of matter. “This year has also seen many Otago researchers receive their first Marsden Fund awards, either a Fast Start early-career award, or a standard award as an established researcher. From friend to foe: How do cancer cells convert the p53 tumour suppressor gene into an oncogene? It was documented in 1927 that whai knowledge and practice was suffering significant loss. Online Medical Crowdfunding (OMC) is an increasingly common way to raise money for healthcare needs not covered by the system. Marsden Fund Fast-Start grants support early career researchers to develop independent research and build exceptional careers in New Zealand. They will use state-of-the-art epigenomic tools to determine whether epigenetic marks play a major role in activation of the innate immune system, leading to gout flares in one brother, but not the other. A fundamental task, with critical practical consequences, is to separate these components in the analysis of any given pattern. The hyperuricaemic phenotype, a common factor in metabolic disease, may have evolved in Pacific ancestors as a protection against malaria,” Professor Merriman explains. The result is that the avian system packs far more firepower than the primate visual system, and is possibly computationally more efficient than that of primates. Dunedin 9016 Rape, Passivity and Permission: A Comparative Analysis of Law on Consent and Reasonable Belief $300,000. It is therefore crucial to ensure that machine learning models do not create or exacerbate inequities in healthcare, due to biased data and unfair algorithms. By steering the optical tweezers, they can gently bump the tiny and frigid clouds together to induce reactive collisions and conduct a chemistry experiment just above zero absolute temperature. This would provide an explanation for the longstanding question about what this "lactation hormone" actually does in males. The best multi-disciplinary meta-analysis, bioinformatics, genetics and spatiotemporal cellular imaging techniques will be used to tackle this central question in evolutionary biology. These compartments may have allowed the diversity of eukaryotes to increase and to exploit different environments. Use our Media Expertise Database to find an Otago researcher for media comment. University of Otago Deputy Vice-Chancellor (Research and Enterprise) Professor Richard Blaikie says this is an excellent outcome for the University, particularly to have the honour of receiving one of the first major Marsden Fund Council Awards. Gout is one of these diseases. In the News | Published: 08 November 2018 08 November 2018. Multiple hairworms are frequently found in a single wētā. What processes drive someone to exploit and intimidate others, ruining lives, and creating massive social impact? Correct termination of transcription is a critical step in gene expression. Overall, the Marsden Fund awarded 134 grants, with Wellington’s 27 accounting for a fifth of them. Some see religion as social glue; others view it as a mechanism for social control. Such data arise in myriad areas, as diverse as epidemiology, ecology, and archaeology. An efficient way to reduce the impact of mis-interactions is to compartmentalise cells. The group of participants they will test is also highly novel: they will recruit a large cohort of individuals from the community (not from prisons) who will undergo extensive careful diagnostic and neurophysiological testing. Explanations about the cognitive basis of this ability make different predictions about how mental state attributions vary across cultures. There were over 1200 applications for support - the highest recorded in the fund's 20-year history. This Marsden grant will use a combination of the latest brain imaging technology and single-neuron recordings to explore the computational mechanisms underlying the processing of complex information (e.g. It starts with a quantitative content analysis of OMC campaigns – to find out the ‘who’, ‘what’ and ‘why’, considering how this relates to New Zealand’s healthcare system and social structure. Search awarded Marsden Fund grants 2008–2017. potential recipients judged most likely to succeed, any such comparison must control for selection bias. Having been the recipient of Marsden grants herself in 1998 and 2003, Gerrard went on to serve as the chair of the Royal Society of New Zealand's Marsden Fund Council from 2012 until 2018. The researchers will determine whether Δ133p53 levels are enriched in slow cycling cells and how they are regulated by microRNAs. It is particularly challenging as nonlinear effects can lead to highly non-dispersive behaviour, such as coherent soliton solutions, and the formation of singularities. This repeated appearance of similar phenotypes is likely to be governed by common genetic and cellular mechanisms. They are one of two large interdisciplinary projects to receive the inaugural Marsden Fund Council Awards with the Marsden Fund (Te Pūtea Rangahau a Marsden) allocating a further $19 million to University of Otago researchers for another 31 projects. These bacteria often partake in a process called interspecies electron transfer, where different steps in respiration are connected between two or more bacteria to form a complete circuit. 11 Turnbull StThorndon, Wellington 6011Aotearoa - New Zealand, © 2021 - Royal Society of New Zealand Te Apārangi, Supporting international research collaboration, President's Address 2019 on redefining research excellence, Te Takarangi: Celebrating Māori publications with Ngā Pae o te Māramatanga, Climate change mitigation options for New Zealand, Climate change implications for New Zealand. Here the team study chemical reactions without any blurring: they prepare the reactants in specific quantum states and collide them at distinct and extremely well-defined energies. About Gary Marsden $960,000. So why does one brother develop gout and not the other? These grants support excellent New Zealand research in the areas of science, engineering, maths, social sciences and the humanities. However, the inability of molecularly targeted drugs to yield durable responses is now thought to be due to a small subpopulation of slow-cycling cells. Nick studies the Antarctic ice sheet and its evolution under a climate increasingly warmed by … It is our task to assess this link. More than $3million in Marsden Fund grants has been awarded to four members of the University of Otago Centre for Neuroendocrinology to research how the brain controls hormones. Marsden recipients tackle climate change, #MeToo and saving the kākāpō Te Herenga Waka—Victoria University of Wellington-led projects have received more than $12.5 million from the Government's Marsden Fund to tackle issues ranging from climate change and renewable energy to #MeToo and gender-based violence—as well as saving the kākāpō from extinction. This database will be used to identify the structure and variation in mental state attributions across cultures and test how ecological and cultural factors explain variation. By simultaneously measuring individual and community units over time, these social conditions will function as “natural experiments,” affording an understanding of the dynamic interplay between religious institutions, cooperation and inequality. The expansion of Austronesian speakers across one third of the world’s surface began out of Asia some 4000 years ago, ending in New Zealand 800 years ago. It will do this by focussing on an area crucial in assessing the nature of Austronesian occupation: the lower and middle Ramu river valley that bordered an inland sea 5-3000 years ago. They will measure reaction rates with unprecedented resolution focusing on elementary reactions that can be modeled with state-of-the-art theory. A maximum Fund for each funding round Search Marsden awards 2008–2017 and test a multi-spectroscopic fiber optic probe of. Of Cohesion and conflict: Testing hypotheses of social and Religious Change in Fiji $ 300,000 for misdiagnosis revealed presence. 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